REFERENCE
GUIDES
The following reference materials provide background information on the HILOmet CYP and WARFARIN DNA Typing Systems. They can be downloaded and printed for reference.
HILOmet CYP DNA Typing System for Diagnosis and Prevention of Adverse Drug Reactions (PDF Document)
HILOmet WARFARIN DNA Typing System for DNA-Guided Warfarin Management (PDF Document)
Enhancing Coumadin® Safety and Individualizing Management with DNA Typing (PDF Document)
CYTOCHROME P450 GENES AND METABOLISM OF COMMON DRUGS TESTED BY THE HILOmet DNA TYPING SYSTEM
2D6 |
2C9 |
2C19 |
Beta
Blockers |
Thromboembolism
|
Proton
Pump Inhibitors |
Propranolol
(Inderal®) |
Warfarin (Coumadin®) |
Omeprazole
(Prilosec®) |
Metoprolol
(Lopressor®) |
Angiotensin
II Blockers |
Lansoprazol
(Prevacid®) |
Antidepressants |
Losartan
(Cozaar®) |
Esomeprazole
(Nexium®) |
Amitriptyline
(Elavil®) |
Irbesartan
(Avapro®) |
Anti-epileptics |
Mirtazapine
(Remeron®) |
Glitazones |
Phenytoin
(Dilantin®) |
Fluvoxamine
(Luvox®) |
Rosiglitazone
(Avandia®) |
Diazepam
(Valium®) |
Duloxetine
(Cymbalta®) |
Pioglitazone
(Actos®) |
Antidepressants |
Venlaxafine
(Effexor® XR) |
Sulfonylureas |
Escitalopram
(Lexapro®) |
Paroxetine
(Paxil®) |
Glipizide
(Glucotrol®) |
Citalopram
(Celexa®) |
Antipsychotics |
Glimepiride
(Amaryl®) |
|
Haloperidol
(Haldol®) |
NSAIDs |
|
Aripiprazole (Abilify®) |
Ibuprofen
(Advil®) |
|
| Risperidone (Risperdal®) |
Naproxen
(Naprosyn®) |
|
Olanzapine (Zyprexa®) |
Antidepressants |
|
ADHD |
Fluoxetine
(Prozac®) |
|
Atomoxetine
(Strattera®) |
Sertraline
(Zoloft®) |
|
Pain |
|
|
Codeine |
|
|
Color Key for Medical
Specialty Use
Yellow |
Neuropsychiatric and Pain drugs |
Green |
Cardiovascular drugs |
Blue |
Diabetes and Internal
Medicine drugs |
